GPI-Phospholipase D Pure 15 50ug

产品编号：BD-610810 品牌：BD-Pharmingen 原厂货号：610810
产品分类：抗体 > 一抗 > 蛋白特异性一抗
应用分类：

包装：

50ug

运保温度:

Store undiluted at -20°C.

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描述：

Glycosylphosphatidylinositol (GPI)-anchored proteins are involved in the regulation of numerous cell-surface activities including the

complement cascade, activation of plasminogen, T-cell activation, cell-to-cell adhesion, and macromolecule transport through the membrane.

GPI-containing proteins are very abundant at the caveolae. GPI-specific phospholipase D (GPI-PLD) hydrolyzes the covalently bound GPI

moiety which functions as an anchor for many cell-surface proteins. Present at high levels in the plasma, GPI-PLD is also secreted by some

cell types in culture. This protein releases the GPI-anchored, complement regulatory protein decay accelerating factor (DAF) from HeLa cells,

as well as the basic fibroblast growth factor (bFGF)-bound heparin sulfate proteoglycan from bone marrow stromal cells. GPI-PLD contains

Ca2+ and Zn2+ binding sites and bears some further structural and perhaps functional similarities to the integrins.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at -20°C.