AKAP220 Pure 13/AKAP220 150ug

产品编号：BD-610705 品牌：BD-Pharmingen 原厂货号：610705
产品分类：抗体 > 一抗 > 蛋白特异性一抗
应用分类：

包装：

运保温度:

Store undiluted at -20° C.

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描述：

The type II cAMP-dependent Protein Kinase (PKA) is compartmentalized within the cell. To maintain this localization of type II PKAs, the

regulatory subunit (RII) interacts with RII-anchoring proteins. For instance, attachment of type II PKA to the cytoskeleton occurs through the

binding of RII to microtubule associated-protein 2. In brain, several proteins have been identified as PKA type II anchoring proteins and form

a family named AKAP (A-Kinase Anchor Proteins). AKAP220 is a protein of 1129 amino acids with a PKARII binding site and a CRL motif

at the COOH terminus, characteristic of peroxisomal proteins. AKAP220 mRNA is expressed ubiquitously with the highest levels in testis and

brain. Immunolocalization studies confirmed the peroxisomal distribution of both AKAP220 and PKARII in a cell line derived from rat

Sertoli cells.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.