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Hu E2A-Pbx1 Pure G289-1 100ug

  • 产品编号:BD-556021      品牌:BD-Pharmingen       原厂货号:556021
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装: 100ug
运保温度: Store undiluted at 4°C.
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描述:

Reacts with E2A-Pbx1, a chimeric gene product of approximately 90 kDa which is the result of t(1,19) (q23;p13.3) chromosomal 
translocation. Sequences of Pbx1 from chromosome 1 are juxtaposed adjacent to sequences of the E2A gene on chromosome 19. The 
translocation results in the transcription of a unique chimeric protein E2A-Pbx1 with an amino acid sequences not present on E2A or Pbx 
alone. E2A-Pbx1 is found only in cells with the t(1,19) translocation. It is detectable in the nucleus of 697 cell line (a pre-B cell line). 
E2A-Pbx1 is considered to be an oncoprotein, however, the oncogenic mechanism has not been fully elucidated.


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before
discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C.
 


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