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Hu CD23 Pure M-L233 500ug

  • 产品编号:BD-555708      品牌:BD-Pharmingen       原厂货号:555708
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装: 500ug
运保温度: Store undiluted at 4°C.
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描述:

The M-L233 antibody reacts with the low affinity receptor for human IgE, FcεRII/CD23. CD23 is a type II membrane protein which can be
expressed by B cells, monocytes, macrophages, eosinophils, platelets, and dendritic cells. CD23 can mediate IgE-dependent cytotoxicity and
phagocytosis by macrophages and eosinophils. Soluble CD23 (sCD23) can be released by CD23+ cells as a result of proteolytic cleavage of
membrane CD23. Larger fragments of sCD23 (e.g., 37-25 kDa) retain their IgE-binding capacity whereas smaller fragments (i.e., ≤ 12 kDa) do
not. Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types.


注意事项:


1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before
discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C.


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