Description: This Ly9ab3 monoclonal antibody reacts with mouse CD229 (also known as Ly9), an approximately 120-kDa member of the Signaling Lymphocyte Activation Molecule (SLAM) immunoglobulin superfamily. This type I transmembrane glycoprotein is expressed on a variety of immune cell types, including thymocytes, hematopoietic stem cells, macrophages, T and B lymphocytes, regulatory T cells, and natural killer cells. CD229 has been shown to interact with the adaptor proteins SLAM-associated protein (SAP) and EAT-2. This antibody recognizes both Ly9 alleles, Ly9.1 and Ly9.2.
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