b-Estradiol: Almost insoluble in water(50 mg/ml-clear, colorless solution). Freely soluble in alcohol; soluble in acetone, dioxane, other organic solvents; solutions of fixed alkali hydroxides; sparingly soluble in vegetable oils; soluble in methanol:CHCl3 (1:1)
b-Estradiol-3-Benzoate: Soluble in alcohol, acetone, dioxane; slightly soluble in ether, vegetable oils.
b-Estradiol-17-enanthate: Soluble in ethanol, acetone, dioxane and chloroform; sparingly soluble in vegtable oils; practically insoluble in water.
Other forms: soluble in alcohol, acetone, dioxane; slightly soluble in vegetable oil; slightly soluble in aqueous buffers.
Description:Potent mammalian estrogenic hormone produced by the ovary. Triggers the production of gonadotropins leading to ovulation.
Availability:
Catalog Number
Description
CAS #
Molecular Formula
Size
101656
b-Estradiol
50-28-2
C18H24O2
250 mg
1 gm
5 gm
25 gm
100 gm
194564
b-Estradiol, cell culture reagent, g-irradiated
50-28-2
C18H24O2
1 mg
194565
b-Estradiol, cell culture reagent
50-28-2
C18H24O2
250 mg
1 gm
5 gm
25 gm
157943
b-Estradiol 17-Acetate
1743-60-8
C20H26O3
250 mg
1 gm
5 gm
190411
b-Estradiol 3-benzoate
50-50-0
C25H28O3
200 mg
1 gm
5 gm
157944
b-Estradiol 3-benzoate 17-n-butyrate
63072-18-2
C29H34O4
1 gm
5 gm
10 gm
190458
b-Estradiol 17-cypionate
313-06-4
C26H36O3
250 mg
1 gm
5 gm
190412
b-Estradiol Diacetate
3434-88-6
C22H28O4
100 mg
250 mg
500 mg
1 gm
5 gm
190413
b-Estradiol Dipropionate
113-38-2
C24H32O4
250 mg
500 mg
1 gm
5 gm
25 gm
190414
b-Estradiol 17-enanthate
4956-37-0
C25H36O3
100 mg
250 mg
1 gm
195052
b-Estradiol 17-Hemisuccinate
7698-93-3
C22H28O5
1 mg
10 mg
50 mg
195050
b-Estradiol 3-methyl ether
1035-77-4
C19H26O2
100 mg
250 mg
1 gm
157945
b-Estradiol 17-propionate
3758-34-7
C21H28O3
1 gm
5 gm
10 gm
157946
b-Estradiol 3-sulfate 17-glucuronide
10392-35-5
C24H30O11K2
1 mg
5 mg
25 mg
190415
b-Estradiol 17-valerate
979-32-8
C23H32O3
100 mg
250 mg
1 gm
5 gm
References:
Merck Index,12th Ed., No. 3746
MacCorquodale, D.W., et al.,J. Biol. Chem.,v. 115, 435 (1936).
Butenandt, A. and Georgens, C.,Z. Physiol. Chem.,v. 248, 129 (1937)
Eder, U., et al.,Ber,v. 109, 2948 (1976)
Oppolzer, W., and Roberts, D.A.,Helv. Chim. Acta,v. 63, 1703 (1980).
Lievertz, R.W.,Am. J. Obstet. Gynecol.,v. 156, 1289 (1987).
Slikker, W., et al.,J. Chromatog.,v. 224, 205 (1981).
Kuhnz, W., et al.,Arzneimittel-Forsch.,v. 43, 966 (1993).
Studd, J.W.W., et al.,Brit. J. Obstet. Gynecol.,v. 101, 787 (1994).
Salole, E.G.,Anal. Profiles Drug Subs.,v. 15, 283-318 (1986).
Data for Biochemical Research,3rd Ed., p. 197 (1986).
Beato, M., "Gene regulation by steroid hormones."Cell,v. 56, 335-344 (1989).
Gorski, J., et al., "Evolution of a model of estrogen action."Recent Prog. Horm. Res.,v. 42, 297-329 (1986).