CD19 MicroBeads, human

产品编号：130-050-301 品牌：MACS美天旎原厂货号：130-050-301
产品分类：生化和细胞分析 > 微珠和磁珠 > 细胞分选磁珠 > 分离人细胞
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包装：

运保温度:

Store protected from light at 2−8 °C.

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描述：

CD19 MicroBeads were developed for positive selection or depletion of CD19+ B cells from different cell sources such as human PBMCs, bone marrow, lymphoid tissues, or cell cultures.

原厂资料：

Background information

As a B cell lineage marker, the CD19 antigen is expressed from the early pro-B cell stage to the B cell lymphoblast stage, but the expression is down-regulated upon B cell maturation to plasma cells. The CD19 antigen is further expressed on most malignant B cells and on a subset of follicular dendritic cells.

Downstream applications

Isolated CD19+ B cells were used for studies on immunoglobulin production, such as IgE synthesis and secretion, chemotaxis assays, or mixed lymphocyte reactions. Positively selected CD19+ B cells were also used for molecular studies such as gene expression profiling. For the analysis of minimal residual diseases in B cell malignancies, enrichment of B cells increases the sensitivity of detection.

Columns

For positive selection: MS, LS, XS, or autoMACS® Columns. For depletion: LD, CS, D, or autoMACS Columns.

注意事项：

Reagents contain sodium azide. Under acidic conditions sodium azide yields hydrazoic acid, which is extremely toxic. Azide compounds should be diluted with running water before discarding. These precautions are recommended to avoid deposits in plumbing
where explosive conditions may develop.