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小牛胸腺DNADeoxyribonucleic Acid Sodium Salt From Calf Thymus

 
包装: 50 mg
运保温度: 2-8°C
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描述:

Sodium Salt
From Calf Thymus

Highly Polymerized.
White, fibrous material
Protein <3% (Lowry)

 

Description: DNA is a polynucleotide. It is an essential component of chromosomes in cell nuclei. It is the carrier of genetic material. It contains information in chemical code to direct the development of the cell according to its inheritance.1

The purine and pyrimidine bases of the nucleosides are primarily adenine, guanine, cytosine and thymine. The sugar is D-2-deoxyribose. The nucleosides are linked together by phosphates in diester linkage from the 3'-hydroxyl of one sugar to the 5'-hydroxyl of the next. The repeating sugar-phosphate linkage forms the backbone of the single polynucleotide strand which is the primary structure of DNA. Chemical analysis of DNA from different species show that the purine content is equal to the pyrimidine content; adenine content equal to thymine; guanine equal to cytosine.1

In the Watson-Crick model of its secondary structure (based on chemical analysis and x-ray studies), DNA consists of two polynucleotide chains forming right-handed helices coiled around the same axis with the sequence of atoms in the two sugar-phosphate backbones running in opposite direction. Two major families of right-handed helix were proposed. A-DNA and B-DNA, each having its own intrinsic restrictions on chain-folding and structure. B-DNA is believed to be the predominant form in biological systems. The purine and pyrimidine bases are inside the helical structure formed by the sugar phosphate backbones; those on one chain form hydrogen bonds to those on the other. Adenine in one chain is always bonded to thymine in the complementary chain by hydrogen bonds; similarly guanine is bonded to cytosine. The linear sequence of bases in one strand completely determines the sequence in the complementary strand. Thus each strand can serve as a template for the replication of the original DNA molecule. DNA also acts as a template in the formation of ribonucleic acids, q.v., which play a fundamental role in the synthesis of proteins in the cell.1

Another form of DNA, termed Z-DNA, is also known. Its structure is an antiparallel double helix with Watson-Crick base pairing, but it is a left-handed helix with the ribose-phosphate backbone following a zig-zag course.

中文名称:小牛胸腺DNA

中文同义词:小牛胸腺DNA;脱氧核糖核酸(由小牛胸腺提取);脱氧核糖核酸(小牛胸腺)DNA;小牛胸腺DNA 脱氧核糖核酸钠盐, CALF THYMUS


注意事项:

Polymerization: "Highly Polymerized" DNA is DNA which has not undergone any additional processing after isolation. "Not Highly Polymerized" DNA is DNA which may have gone through some denaturization after isolation.

 


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