CD45 leukocyte common antigen (LCA) belongs to the family of at least four isoforms of membrane glycoproteins (220, 205, 190, 180kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellular portion of these molecules has protein phosphatase activity and is involved in regulation of transmembrane signals.
CD45 Human Recombinant (aa 1102-1150) expressed in E.coli, shows a 33 kDa band on SDS-PAGE (Including GST).
The CD45 is purified by proprietary chromatographic techniques.