Leukocyte associated protein consists of two polypeptide chains with molecular weights 95 and 170kDa. The moleculae functions as a cell surface receptor for the C3bi complement fragment. It belongs to family of heterodimeric proteins (designated CD11) which share a common beta chain CD18 of 95kDa. The alpha chain component of the leukocyte associated antigen is expressed on granulocytes, monocytes and macrophages.
CD11b Human Recombinant (aa 936-1154) expressed in E.coli, shows a 52 kDa band on SDS-PAGE.
The CD11b is purified by proprietary chromatographic techniques.
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