CD23 is a 45kDa glycoprotein, which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma.
CD23 Human Recombinant (aa 48-248) expressed in E.coli, shows a 48 kDa band on SDS-PAGE.
The CD23 is purified by proprietary chromatographic techniques.