The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.
FUNCTION:SwissProt: Q9NQ66 # The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. COFACTOR:Calcium. SIZE:1216 amino acids; 138567 Da SIMILARITY:SwissProt: Q9NQ66 ## Contains 1 C2 domain. & Contains 1 PI-PLC X-box domain. & Contains 1 PI-PLC Y-box domain. MISCELLANEOUS:The receptor-mediated activation of PLC-beta-1 is mediated by two G-protein alpha subunits, alpha-Q and alpha-11.
Product Usage Statements
Quality Assurance
routinely evaluated by immunoprecipition of PLCβ-1 from a bovine brain membrane preparation, subsequent immunoblotting performed by the antibody
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
2 years at -20°C
Packaging Information
Material Size
100 µg
原厂资料：
Key Spec Table
Species Reactivity
Key Applications
Host
Format
Antibody Type
B, R, M, H
IP
M
Purified
Monoclonal Antibody
Description
Catalogue Number
05-164
Brand Family
Upstate
Trade Name
Upstate
Description
Anti-PLCβ-1 Antibody
Product Information
Format
Purified
Presentation
100mM Tris-glycine, pH 7.4, 0.15M NaCl with 0.05% sodium azide
Applications
Application
Detect PLCβ-1 using this Anti-PLCβ-1 Antibody validated for use in IP.
Key Applications
Immunoprecipitation
Biological Information
Immunogen
Mixed monoclonal antibodies raised against purified bovine PLCβ-1
Host
Mouse
Specificity
PLCβ-1, also recognize the 100kDa and 41kDa fragments of PLCβ-1.1
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.
FUNCTION:SwissProt: Q9NQ66 # The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. COFACTOR:Calcium. SIZE:1216 amino acids; 138567 Da SIMILARITY:SwissProt: Q9NQ66 ## Contains 1 C2 domain. & Contains 1 PI-PLC X-box domain. & Contains 1 PI-PLC Y-box domain. MISCELLANEOUS:The receptor-mediated activation of PLC-beta-1 is mediated by two G-protein alpha subunits, alpha-Q and alpha-11.
Product Usage Statements
Quality Assurance
routinely evaluated by immunoprecipition of PLCβ-1 from a bovine brain membrane preparation, subsequent immunoblotting performed by the antibody
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
京公网安备11010802025653 版权所有：北京逸优科技有限公司
