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Anti-ADP-Ribosylation Factor 6, clone 6A

  • 产品编号:merck-m-05-1149      品牌:millipore       原厂货号:05-1149
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装: ea
运保温度: 2-8ºC
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描述:

Key Spec Table

 

Species Reactivity Key Applications Host Format Antibody Type
H WB M Purified Monoclonal Antibody

Description 
Catalogue Number 05-1149
Replaces MAB1131
Description Anti-ADP-Ribosylation Factor 6 Antibody, clone 6ARF01
Alternate Names
  • ADP-ribosylation factor 6
Background Information ADP-Ribosylation Factor 6 (ARF6) is a GTP-binding protein that functions as a regulator of cytoskeleton remodeling and endocytic recycling. ARF6 is an allosteric activator of cholera toxin catalytic subunit, an ADP-ribosyltransferase. It may also be involved in the modulation of vesicle budding and uncoating with the Golgi apparatus.

Product Information 
Format Purified
Control
  • NIH/3T3 Cell Lysate
Presentation Purified monoclonal IgG ascites in 10 mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.

Applications 
Application Anti-ADP-Ribosylation Factor 6 Antibody, clone 6ARF01 is a Mouse Monoclonal Antibody for detection of ADP-Ribosylation Factor 6 also known as ADP-ribosylation factor 6 & has been validated in WB.
Key Applications
  • Western Blotting

Biological Information 
Immunogen Recombinant human ARF6 protein.
Clone 6ARF01
Concentration Please refer to the Certificate of Analysis for the lot-specific concentration.
Host Mouse
Specificity Recognizes ADP-ribosylation factor (ARF) 6.
Isotype IgG
Species Reactivity Human
Species Reactivity Note Reacts with human.
Antibody Type Monoclonal Antibody
Entrez Gene Number
Gene Symbol
  • DKFZp564M0264
Purification Method Protein G chromatography
UniProt Number
UniProt Summary FUNCTION: SwissProt: P62330 # GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
SIZE: 175 amino acids; 20082 Da 
SUBUNIT: Interacts with ARHGAP21, DDEF2, PIP5K1C and UACA.
SIMILARITY: SwissProt: P62330 ## Belongs to the small GTPase superfamily. Arf family.

Product Usage Statements 
Quality Assurance Evaluated in Western Blot on NIH/3T3 cell lysates.
Western Blot Analysis: 1:500 dilution of this antibody detected ARF6 in 10 µg of NIH/3T3 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information 
Storage Conditions Maintain refrigerated at 2-8ºC in undiluted aliquots for up to 12 months from date of receipt.

Packaging Information 
Material Size 100 µg

 


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