SG2NA, also known as Striatin 3, was identified as a human cancer auto-antigen and has not been implicated in vesicular trafficking and signal tranduction. It is highly related to striatin and zinedin (striatin 4). It is a cytoplasmic scaffolding protein that binds to Calmodulin and PP2A A and C subunits as well as the human homolog of the yeast protein, Mob1, which appears to modulate PP2A activity.
Anti-SG2NA Antibody is an antibody against SG2NA for use in WB, IC & IP.
Key Applications
Western Blotting
Immunoprecipitation
Immunocytochemistry
Application Notes
Immunocytochemistry: A previous lot of this antibody was used in immunocytochemistry at a 1:500 dilution.
Immunoprecipitation: A previous lot of this antibody was used in IP; 3 μL is a recommended as starting point for immunoprecipitation.
Optimal working dilutions must be determined by end user.
Biological Information
Immunogen
Synthetic peptide from SG2NA.
Host
Mouse
Specificity
Reacts with SG2NA. No cross reactivity with striatin.
FUNCTION: Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
SUBUNIT: Interacts with protein phosphatase 2A (PP2A) (Potential).
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity).
ALTERNATIVE PRODUCTS: 2 named isoforms [FASTA] produced by alternative splicing. Additional isoforms seem to exist. Name Beta
Isoform ID Q13033-1
This is the isoform sequence displayed in this entry.
Name Alpha
Isoform ID Q13033-2
Features which should be applied to build the isoform sequence: VSP_006786.
SIMILARITY: Belongs to the WD repeat striatin family.
SIMILARITY: Contains 6 WD repeats.
CAUTION: Was originally (PubMed:7864889) thought to be nuclear.
Product Usage Statements
Quality Assurance
Routinely evaluated by Western Blot on L6 lysates.
Western Blot Analysis: 1:500 dilution of this lot detected SG2NA on 10 μg of L6 lysates.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Stable at -20°C in undiluted aliquots for up to 1 year from date of receipt. For long-term storage, may be stored at -80°C.
Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size
100 µL
原厂资料：
Key Spec Table
Species Reactivity
Key Applications
Host
Format
Antibody Type
H, M, R
WB, IP, ICC
M
Ascites
Monoclonal Antibody
Description
Catalogue Number
05-1115
Replaces
MAB5464
Description
Anti-SG2NA Antibody
Alternate Names
Cell-cycle autoantigen SG2NA
Striatin 3
Background Information
SG2NA, also known as Striatin 3, was identified as a human cancer auto-antigen and has not been implicated in vesicular trafficking and signal tranduction. It is highly related to striatin and zinedin (striatin 4). It is a cytoplasmic scaffolding protein that binds to Calmodulin and PP2A A and C subunits as well as the human homolog of the yeast protein, Mob1, which appears to modulate PP2A activity.
Anti-SG2NA Antibody is an antibody against SG2NA for use in WB, IC & IP.
Key Applications
Western Blotting
Immunoprecipitation
Immunocytochemistry
Application Notes
Immunocytochemistry: A previous lot of this antibody was used in immunocytochemistry at a 1:500 dilution.
Immunoprecipitation: A previous lot of this antibody was used in IP; 3 μL is a recommended as starting point for immunoprecipitation.
Optimal working dilutions must be determined by end user.
Biological Information
Immunogen
Synthetic peptide from SG2NA.
Host
Mouse
Specificity
Reacts with SG2NA. No cross reactivity with striatin.
FUNCTION: Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
SUBUNIT: Interacts with protein phosphatase 2A (PP2A) (Potential).
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity).
ALTERNATIVE PRODUCTS: 2 named isoforms [FASTA] produced by alternative splicing. Additional isoforms seem to exist. Name Beta
Isoform ID Q13033-1
This is the isoform sequence displayed in this entry.
Name Alpha
Isoform ID Q13033-2
Features which should be applied to build the isoform sequence: VSP_006786.
SIMILARITY: Belongs to the WD repeat striatin family.
SIMILARITY: Contains 6 WD repeats.
CAUTION: Was originally (PubMed:7864889) thought to be nuclear.
Product Usage Statements
Quality Assurance
Routinely evaluated by Western Blot on L6 lysates.
Western Blot Analysis: 1:500 dilution of this lot detected SG2NA on 10 μg of L6 lysates.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Stable at -20°C in undiluted aliquots for up to 1 year from date of receipt. For long-term storage, may be stored at -80°C.
Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
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