Recombinant Human Protein Phosphatase 1, Catalytic Subunit Alpha(PPP1CA)

• 产品编号：enz-165-1ug      品牌：Prospec       原厂货号：enz-165-1ug
• 产品分类：蛋白质检测与分析 > 蛋白质，多肽和酶 > 磷酸酶及其抑制剂
• 应用分类：

描述：

PPM1G is part of the PP2C family of Ser/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways. PPM1G is accountable for the dephosphorylation of Pre-mRNA splicing factors, an important factor for the formation of functional spliceosome. PPM1G regulates cell cycle progression. 
PPM1G mediates histone dephosphorylation/exchange in response to DNA damage or checkpoint recovery in higher eukaryotes. 
The degradation of p21/WAF1 induced by PPM1G is mediated in a proteasome-dependent manner. 
Protein phosphatase 1G regulates assembly and function of the beta-catenin degradation complex.
PPM1G Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 566 amino acids (1-546) and having a molecular mass of 61.4 kDa. 
The PPM1G is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
 

原厂资料：