IFN-gamma produced by lymphocytes activated by specific antigens or mitogens.
IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Interferon-g Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 143 amino acids fragment (24-166) and having a molecular mass of 21.28 kDa with an amino-terminal hexahistidine tag.
The IFN-g-His is purified by proprietary chromatographic techniques.