Recombinant Human Growth and Differentiation factor 15 H-Variant(GDF5 H)

产品编号：cyt-335-1mg 品牌：Prospec 原厂货号：cyt-335-1mg
产品分类：蛋白质检测与分析 > 蛋白质，多肽和酶 > 细胞因子和生长因子 > 其它细胞因子和生长因子
应用分类：细胞培养产品与服务 > 哺乳动物细胞培养 > 细胞因子
　　　　　细胞培养产品与服务 > 哺乳动物细胞培养 > 生长因子和纯化蛋白质 > 物种 > 人

包装：

1mg

运保温度:

below -18°C

到货周期：

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描述：

GDF15 is part of the TGF-Beta superfamily that is involved in regulating inflammatory and apoptotic pathways in injured tissues and throughout disease processes. GDF15 is most abundant in the liver. Its expression in liver can be considerably up-regulated in during injury of organs such as liver, kidney, heart and lung. GDF-15 promotes proliferation or growth arrest and differentiation due to differences in cellular differentiation. GDF15 prevents apoptosis in cerebellar granule neurons by activating Akt and inhibiting endogenously active ERK. GDF15 is a novel autocrine/endocrine factor that antagonizes the hypertrophic response and loss of ventricular performance.
GDF15 Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated, Polypeptide chain containing 2x113 amino acids and having a molecular mass of 24.5 kDa.
The GDF15 is purified by proprietary chromatographic techniques.

详细说明


危险品标识:
CAS:
冷链运输标志:
Source:	Escherichia Coli.
Physical Appearance:	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:	GDF15 is lyophilized without additives.
Solubility:	It is recommended to reconstitute the lyophilized GDF15 in sterile 5mM AcOH (acetic Acid) at a concentration of 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability:	Lyophilized GDF15 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GDF15 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Purity:	Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.


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Recombinant Human Growth and Differentiation factor 15 H-Variant(GDF5 H)

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