APOA2 stabilizes the HDL structure by its relationship with lipids, and plays a role in the HDLMetabolism. APOA2 is the 2nd most abundant protein of the high density lipoprotein particles. APOA2 is localized in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in APOA2 gene might cause apolipoprotein A-II deficiency or hypercholesterolemia.
APOA2 Human isolated from Human HDL is a single, glycosylated, polypeptide chain having a molecular mass of 17.38kDa. APOA2 is purified using delipidation and gel permeation chromatographic technique.