Anti-Human CD32 (FcγRII) Blocker is a mouse IgG2b monoclonal antibody purified from concentrated hybridoma culture supernatant by affinity chromatography using Protein A or Protein G Sepharose. CD32 (FcγRII) is a 40 kDa receptor for the Fc region of Immunoglobulin G (IgG). CD32 binds weakly to the Fc portion of monomeric IgG, but efficiently to IgG aggregates and immune complexes. The Fc/FcR interactions may result in non-specific labeling in antibody-based detection and cell separation experiments. This antibody is recommended to block Fc/FcR interactions during negative cell selection.
Product Type:
Cell isolation products
Recommended For:
Blocking non-specific antibody binding to monocytes and other FcγRII+ cells prior to StemSep™ or EasySep™ immunomagnetic selection
Area of Interest:
Immunology
Cell Isolation Product Type:
Reagents
Popular Product Line:
StemSep™
Species:
Human
Intended Use Statement:
FOR RESEARCH USE ONLY. NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES.
ISO Statement:
STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485 MEDICAL DEVICE STANDARDS.
注意事项：
Hazards Identification
Emergency Overview: This product is a potential irritant to eyes, respiratory system, and skin. This product may also be harmful if ingested. Complete toxicological properties have yet to be determined.
Routes of Exposure: Absorbed through skin, eye contact, inhalation, and ingestion.
Potential Health Effects:
Eye: May cause eye irritation.
Skin: May cause skin irritation.
Inhalation: May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.
Chronic Effects/Carcinogenicity: Not Available
OSHA Regulatory Status: Not Available
First Aid Measures
Eyes: In case of contact with eyes, flush thoroughly with water. Call a physician.
Skin: In case of contact with skin, wash the affected area with soap and copious amounts of water. Should irritation occur, contact a physician.
Ingestion: If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation: If inhaled, remove person to fresh air. If breathing becomes difficult, call a physician.
Puncture Wounds: Wash thoroughly with soap and water. Allow to bleed freely. Call a physician.
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