CD49f (also known as α6 integrin) plays a role in cell adhesion and is expressed on a variety of cells. In epidermal and mammary epithelial cells, high expression of CD49f is associated with progenitor and stem cell activity. In the mouse mammary gland, CD49f is the single most important marker in selecting mammary stem and progenitor cells. This antibody reacts with both human and mouse CD49f. This monoclonal antibody was generated from rats immunized with BALB/C mouse mammary tumour cells. The fusion partner was SP2/0 mouse myeloma cells.
Clone Name:
GoH3
Species Reactivity:
Human, Mouse
Host Species:
Rat
Immunogen:
Mouse (BALB/c) mammary tumor cells
Isotype:
IgG2a, kappa
Application:
Flow cytometry
Alternate Names:
α6 Integrin
Product Type:
Antibodies
Recommended For:
Flow Cytometry
Contains:
100 tests in 1 mL aqueous buffered solution containing 0.1% sodium azide and 1% bovine serum albumin
Antibody Type:
Primary antibodies
Area of Interest:
Mammary cell research
Cell Type:
Mammary epithelial cells
Intended Use Statement:
FOR RESEARCH USE ONLY. NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES.
ISO Statement:
STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485 MEDICAL DEVICE STANDARDS.
注意事项：
Hazards Identification
Emergency Overview: Caution, sodium azide is a hazardous and poisonous substance. Sodium azide may react with lead and copper plumbing to form highly explosive metal azides. This product is a potential irritant to eyes, respiratory system, and skin. This product may also be harmful if ingested. Complete toxicological properties have yet to be determined.
Routes of Exposure: Absorbed through skin, eye contact, inhalation, and ingestion.
Potential Health Effects:
Eye: May cause eye irritation.
Skin: May cause skin irritation.
Inhalation: May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Ingestion: May be harmful if swallowed.
Chronic Effects/Carcinogenicity: Not Available
OSHA Regulatory Status: Not Available
First Aid Measures
Eyes: In case of contact with eyes, flush thoroughly with water. Call a physician.
Skin: In case of contact with skin, wash the affected area with soap and copious amounts of water. Should irritation occur, contact a physician.
Ingestion: If swallowed, induce vomiting. Call a physician.
Inhalation: If inhaled, remove person to fresh air. If breathing becomes difficult, call a physician.
Puncture Wounds: Wash thoroughly with soap and water. Allow to bleed freely. Call a physician.
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