Human Granzyme B ELISpot Development Module, 5 Plate (1 KT)

• 产品编号：RD-SEL2906      品牌：R&D       原厂货号：SEL2906
• 产品分类：ELISA及其它免疫分析 > ELISpot及FluoroSpot > ELISpot试剂盒
• 应用分类：

描述：

Molecule Information:  Granzyme B
 

Aliases: CSPB; CTLA-1; CTSGL1; Fragmentin-2; Granzyme-2; GRB; GrzB; GZMB; HLP; SECT

Entrez Gene IDs: 3002 (Human); 14939 (Mouse)

Background: Granzymes 
Granzyme family serine proteases are stored in the granules of cytotoxic T lymphocytes and natural killer cells. Granzymes contain one S1 protease domain and are synthesized as preproproteins. Granzymes are released toward pathogen infected or transformed target cells during cellular immune reactions. Target cell entry by granzymes is through perforin channels. Granzymes trigger apoptosis by caspase-dependent and -independent mechanisms. There are five granzymes (A, B, G, H and K) in human and many more in mouse and rat.

原厂资料：

Molecule Information:  Granzyme B
 

Aliases: CSPB; CTLA-1; CTSGL1; Fragmentin-2; Granzyme-2; GRB; GrzB; GZMB; HLP; SECT

Entrez Gene IDs: 3002 (Human); 14939 (Mouse)

Background: Granzymes 
Granzyme family serine proteases are stored in the granules of cytotoxic T lymphocytes and natural killer cells. Granzymes contain one S1 protease domain and are synthesized as preproproteins. Granzymes are released toward pathogen infected or transformed target cells during cellular immune reactions. Target cell entry by granzymes is through perforin channels. Granzymes trigger apoptosis by caspase-dependent and -independent mechanisms. There are five granzymes (A, B, G, H and K) in human and many more in mouse and rat.

注意事项：

* Sold separately (see Other Reagents Required, below)
** Following an overnight incubation with capture antibody, 2 hour blocking step, and cell stimulation.
*** When using the protocol provided.