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Rat CD3+ T Cell Enrichment Column, Small, Pack of 10 (1 KT)

  • 产品编号:RD-RTCC-10      品牌:R&D       原厂货号:RTCC-10
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描述:

Molecule Information:  CD3

Entrez Gene IDs: 916 (Human); 12503 (Mouse)

Background: CD3 


The T cell receptor (TCR)/CD3 complex consists of two variable antigen-recognition receptor chains (TCR-alpha/TCR-beta or TCR-gamma/TCR-delta) that are non-covalently linked to at least four different invariant chains: CD3 gamma, CD3 delta, CD3 epsilon, and the CD3 zeta chain that exists as either a homodimer or as a heterodimer with its splice-variant the CD3 eta chain. The CD3 complex functions to transduce intracellular signals during TCR antigen recognition. CD3 is expressed early in thymocyte development, and on a subset of NK cells. CD3 epsilon is one of at least three invariant proteins that associate with the variable antigen recognition chains of the T cell receptor and function in signal transduction.


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