Background: IFN-alpha/beta R1
IFN-alpha/beta R1, also known as IFNAR1, is a 120 kDa component of the class II cytokine receptor that contributes to the functional receptor for type I IFNs. IFN-alpha/beta R1 associates with the 100 kDa IFN-alpha/beta R2 component to form a receptor complex that transmits anti-viral and anti-proliferative signals. Down-regulation of the receptor is accomplished by ubiquitination and degradation.
原厂资料:
Molecule Information: IFN-alpha/beta R1
Long Name: Interferon alpha/beta Receptor 1
Aliases: IFNAR1
Entrez Gene IDs: 3454 (Human); 15975 (Mouse)
Background: IFN-alpha/beta R1
IFN-alpha/beta R1, also known as IFNAR1, is a 120 kDa component of the class II cytokine receptor that contributes to the functional receptor for type I IFNs. IFN-alpha/beta R1 associates with the 100 kDa IFN-alpha/beta R2 component to form a receptor complex that transmits anti-viral and anti-proliferative signals. Down-regulation of the receptor is accomplished by ubiquitination and degradation.