Dopa decarboxylase (DDC) is a group II decarboxylase that catalyzes the decarboxylation of aromatic L-amino acids. DDC produces the neurotransmitters dopamine and serotonin from L-Dopa and L-5-hydroxytryptophan, respectively. Deficiency of DDC is associated with severe developmental delay, oculogyric crises and autonomic dysfunction.
Dopa decarboxylase (DDC) is a group II decarboxylase that catalyzes the decarboxylation of aromatic L-amino acids. DDC produces the neurotransmitters dopamine and serotonin from L-Dopa and L-5-hydroxytryptophan, respectively. Deficiency of DDC is associated with severe developmental delay, oculogyric crises and autonomic dysfunction.
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