Long Name: Vitamin D [1,25-Dihydroxyvitamin D3] Receptor
Aliases: NR1I1
Entrez Gene IDs: 7421 (Human)
Background: VDR / NR1I1
Vitamin D Receptor (VDR; NR1I1) is a member of the steroid receptor family related to the PXR and CARs. The natural ligand of VDR is 1, 25 di-hydroxyvitamin D3. VDR is expressed in osteoblasts, osteocytes, osteoclasts, bone, bone marrow, thymus and small intestine. VDR plays critical roles in calcium homeostasis, bone development and mineralization, as well as control of cell growth and differentiation. RXRs are the major partners for VDR since by heterodimerizing with VDR, they increase their DNA-binding affinity and select the correct spacing of direct repeat elements.
原厂资料：
Molecule Information: VDR/NR1I1
Long Name: Vitamin D [1,25-Dihydroxyvitamin D3] Receptor
Aliases: NR1I1
Entrez Gene IDs: 7421 (Human)
Background: VDR / NR1I1
Vitamin D Receptor (VDR; NR1I1) is a member of the steroid receptor family related to the PXR and CARs. The natural ligand of VDR is 1, 25 di-hydroxyvitamin D3. VDR is expressed in osteoblasts, osteocytes, osteoclasts, bone, bone marrow, thymus and small intestine. VDR plays critical roles in calcium homeostasis, bone development and mineralization, as well as control of cell growth and differentiation. RXRs are the major partners for VDR since by heterodimerizing with VDR, they increase their DNA-binding affinity and select the correct spacing of direct repeat elements.
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