Long Name:Interleukin 1 Receptor Accessory Protein-like 1
Aliases:IL-1 R8; TIGIRR-2
Entrez Gene IDs: 11141 (Human)
Background:IL-1 RAPL1
The Interleukin 1 receptor family comprises at least nine members. All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) differs from the other nine members by having only one Ig domain.
Interleukin 1 receptor accessory protein-like 1 (IL-1 RAPL1), also known as IL-1 R8, Oligophenin-4 (OPHN4) and three immunoglobulin domain containing IL-1 receptor-related 2 (TIGIRR-2), is a member of the IL-1 receptor superfamily.
Specificity:Detects human IL‑1 RAPL1/IL‑1 R8 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) IL-1 RI, rhIL-1 RII, rhIL-1 RAcP, rhIL-1 R4, rhIL-1 R5, rhIL-1 Rrp2, rhIL-1 R7, or rhIL-1 RAPL2 is observed.
原厂资料：
Molecule Information:IL-1 RAPL1/IL-1 R8
Long Name:Interleukin 1 Receptor Accessory Protein-like 1
Aliases:IL-1 R8; TIGIRR-2
Entrez Gene IDs: 11141 (Human)
Background:IL-1 RAPL1
The Interleukin 1 receptor family comprises at least nine members. All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) differs from the other nine members by having only one Ig domain.
Interleukin 1 receptor accessory protein-like 1 (IL-1 RAPL1), also known as IL-1 R8, Oligophenin-4 (OPHN4) and three immunoglobulin domain containing IL-1 receptor-related 2 (TIGIRR-2), is a member of the IL-1 receptor superfamily.
Specificity:Detects human IL‑1 RAPL1/IL‑1 R8 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) IL-1 RI, rhIL-1 RII, rhIL-1 RAcP, rhIL-1 R4, rhIL-1 R5, rhIL-1 Rrp2, rhIL-1 R7, or rhIL-1 RAPL2 is observed.
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