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描述:
Insulin-like growth factor I (also known as somatomedin C and somatomedin A) and insulin-like
growth factor II (multiplication stimulating activity or MSA) belong to the family of insulin-like
growth factors that are structurally homologous to proinsulin. Mature IGF-I and IGF-II share
approximately 70% sequence identity. Both IGF-I and IGF-II are expressed in many tissues and
cell types and may have autocrine, paracrine and endocrine functions. Mature IGF-I and IGF-II
are highly conserved (100% identity between human, bovine and porcine proteins) and
exhibit cross-species activity.
原厂资料:
exhibit cross-species activity.
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