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描述:
Human CCL1 was initially identified by subtractive hybridization as a transcript that was
present in a γ/δ T cell line but not in EBVtransformed B cells. Human CCL1 has been
assumed to be a homologue of the mouse TCA3. While the two proteins share only
approximately 42% amino acid sequence identity, both chemokines contain an extra pair
of cysteine residues not found in most other chemokines. Human CCL1 and mouse TCA3 also
share significant sequence homology in the 5’ flanking region of their genes.
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