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描述:
Endocrine gland-derived vascular endothelial cell growth factor (EG-VEGF; also called
prokineticin-1) is a member of the prokineticin family of secreted proteins whose
distinguishing structural motif involves 10 cysteines that form five intrachain disulfide
bonds, creating a “colipase fold”. The mouse EG-VEGF precursor is 105 amino acids in
length and contains a 19 aa signal sequence plus an 86 aa mature segment. There are
no potential N-linked glycosylation sites, and the secreted molecule is a monomer that is
approximately 10 kDa in size. The mature region in mouse is 93% and 87% aa identical to
the mature regions in rat and human, respectively.
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