Recombinant Human VEGF-C Protein, CF (25 UG)

包装：

运保温度:

at ambient temperature

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描述：

Vascular endothelial growth factor C (VEGF-C) and VEGF-D constitute a VEGF sub-family that

share the conserved VEGF homology domain (VHD) with other VEGF family members but are

distinguished by their preferential formation of noncovalent homodimers. Both VEGF-C and -D

have long N- and C-terminal propeptide extensions. The VEGF-C propeptide undergoes stepwise

proteolytic processing to generate ligands with increasing affinity for VEGF-R3. However, only

the fully processed VEGF-C containing just the VHD can bind VEGF-R2. None of the VEGF-C

forms have appreciable affinity for VEGF-R1. VEGFC is expressed in multiple adult human tissues,

most prominently in lymph nodes, heart, placenta, ovary, and small intestine.

原厂资料：