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Recombinant Human DPPIV/CD26 Protein, CF (10 UG)

 
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描述:

Molecule Information:  DPPIV/CD26

Long Name:  Dipeptidyl-peptidase IV

Aliases: CD26; DPP4

Entrez Gene IDs: 1803 (Human); 13482 (Mouse)

Background: DPPIV 
Dipeptidyl peptidase IV (DPPIV/CD26) is a serine exopeptidase that releases Xaa-Pro dipeptides from the N-terminus of proteins and peptides. It plays an important role in T-cell costimulation, chemokine biology, type II diabetes and tumor biology. There are at least 15 DPPIV-related human genes. Some function as enzymes, including DPP8, DPP9, fibroblast activation protein (FAP), prolyl endopeptidase (PREP), and N-acylaminoacyl-peptide hydrolase (APEH) while others (DPP6/DPPX and DPP10/DPRP3) may have lost their protease properties but acquired novel functions. For example, DPP6 is a critical component of neuronal A-type K+ channels.


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