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Recombinant Human Ret Protein, CF (50 UG)

 
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描述:

Molecule Information:  Ret

Long Name: Proto-oncogene Tyrosine-protein Kinase Receptor Ret

Entrez Gene IDs: 5979 (Human); 19713 (Mouse)

Background: Ret 
The GDNF family members (GDNF, neurturin, artemin, and persephin) signal through multicomponent receptors that consist of the Ret receptor tyrosine kinase and one of four glycosyl-phosphatidylinositol (GPI)-linked ligand-binding subunits (GFR alpha-1-4). GFR alpha-1, -2, -3 and -4 are the preferred ligand-binding subunits for GDNF, neurturin, artemin, and persephin, respectively. The Ret tyrosine-kinase receptor is encoded by the c-ret proto-oncogene. Human and mouse Ret share 83% amino acid sequence homology.


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