Mouse cardiotrophin-1 (CT-1) is a 21.3kD cytokine which is expressed in heart and several other mouse tissues. It was originally identified by its ability to induce cardiac myocyte heterotrophy in vitro.
Cardiotrophin-1 acts as a hepatocyte stimulating factor and induces hepatic expression of acute phase proteins. It also acts to inhibit the differentiation of mouse embryonic stem cells.
Target Species
Mouse
Product Form
Purified Recombinant Protein - lyophilised
Preparation
Recombinant protein expressed in E. coli.
Preservative Stabilisers
None present
Protein Molecular Weight
21.3kD (202 amino acid sequence)
Reconstitution
Reconstitute with 20ul distilled water
Purity
>98% by SDS PAGE and HPLC analysis
Activity
1 x 106 units/mg
Approx. Protein Concentrations
0.5 mg/ml
Buffer Solution
TRIS buffered saline
Note
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Serotec recommend that the vial is gently mixed after reconstitution.
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