Recombinant RANK Ligand (RANKL) is a bioactive protein intended for use in cell culture applications. RANKL is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. RANKL was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis.
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注意事项：
For Research Use Only. Not for use in diagnostic procedures.
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