Recombinant Human Transforming Growth Factor β 1 (TGFB1) is a bioactive protein intended for use in cell culture applications. TGFB1 is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB1 acts synergistically with TGF-α in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB1 activation and signaling may result in apoptosis.
• High purity—no interference from other proteins or contaminants • High biological activity—more results with less protein • Proven compatibility—Gibco® proteins bioassayed with Gibco® media
High Purity Recombinant Bioactive Protein Recombinant Human Transforming Growth Factor β 1 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.
High Biological Activity In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Transforming Growth Factor β 1 (TGFB1) specific activity is determined by measuring the TGFB1 dose-dependent inhibition of proliferation of mouse HT-2 cells stimulated with mouse IL-4.
Proven Compatibility Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.
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For Research Use Only. Not for use in diagnostic procedures.
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