收藏本站
热门搜索: A3500  E1910  A1360  25200056  dmem  

CYP1A2 BACULOSOMES PLUS 0.5 NMOL

 
包装:
运保温度: Store at -80°C
到货周期: 登录后查看
标准价: ¥客户可见
会员价: ¥客户可见
积分: 客户可见
 
登录之后可加入购物车购买,请您 
对比 收藏

运费与支付说明:

1.含干冰类产品有运费;

2. 必须现金付款或有信用额度的会员才可以直接发货,否则需要等待现金付款信息。

描述:

Cytochrome P450 BACULOSOMES® Plus Reagents are microsomes prepared from insect cells infected with recombinant baculovirus containing a human CYP450 isozyme, as well as human cytochrome P450 reductase.
• Single human P450 isozyme for detailed drug metabolism studies
• High specific activity increases dynamic range and sensitivity
• No background metabolism for clear results

Single Overexpressed Human CYP450 Isozyme
CYP450 BACULOSOMES® Plus Reagents offer a distinct advantage over Human Liver Microsomes (HLMs) in that only one CYP450 isozyme is expressed, thereby preventing metabolism by other CYP450s or other classes of drug metabolizing enzymes.

High Activity Results in Increased Sensitivity
Compound rankings based on metabolism and inhibition profiles observed with CYP450 BACULOSOMES® Plus Reagents are very similar to those seen with HLMs for most compounds tested. However, CYP450 BACULOSOMES® Plus Reagents activity and metabolic rates with most substrates is significantly higher than those seen with HLMs. This results in a broad dynamic range and high sensitivity in assays utilizing CYP450 BACULOSOMES® Plus Reagents. The high level of activity and reproducibility of the enzyme component observed in the reaction with most probe substrates makes CYP450 BACULOSOMES® Plus Reagents well suited to high-throughput screening formats.

High Signal to Noise Ratio
No background metabolism by endogenous insect CYP450s has been detected with any of the Vivid® probe substrates tested so far.

Applications: isozyme identification, DMPK analysis, isozyme-specific metabolism, and inhibition screening

 


注意事项:

For Research Use Only. Not for any animal or human therapeutic or diagnostic use.


相关图片

说明书

参考文献

本产品可用于的实验

购此产品的人还购买了
最近浏览产品

京ICP备15036693号-2    京公网安备11010802025653    版权所有:北京逸优科技有限公司       0.04

 纠 错