Luciferin-β-galactoside is a substrate for the commonly used reporter enzyme β-galactosidase. The substrate is cleaved by β-galactosidase to form luciferin and galactose. When used in a model system expressing firefly luciferase, the luciferin is then utilized in a firefly luciferase reaction to generate light.
VivoGlo™ In Vivo Imaging Substrates are provided in cooperation with Xenogen Corporation and Caliper Life Sciences for use in in vivo bioluminescence imaging applications.
Features - Benefits
Highest Quality Substrates: Eliminate potential interference in assays due to the presence of endotoxins.
Assured Product Integrity: Most products are packaged in amber vials with septa to ensure product integrity as well as offer ease of dilution and use for imaging experiments. Product is packaged with fine tolerances to minimize the need to weigh substrates.
Flexibility and Convenience: Available in multiple sizes to accommodate a variety of experimental settings.
References
Wehrman T.S. et al. (2006) Nature Methods3, 295–301.