Luciferase genes from the North American firefly (Photinus pyralis) and from other beetles are commonly used as light-emitting reporters in cellular and animal models. VivoGlo™ Luciferin is the potassium salt of d-luciferin, the firefly luciferase substrate capable of generating light when a suitable model is used.
VivoGlo™ In Vivo Imaging Substrates are provided in cooperation with Xenogen Corporation and Caliper Life Sciences for use in in vivo bioluminescence imaging applications.
Features - Benefits
Highest Quality Substrates: Eliminate potential interference in assays due to the presence of endotoxins.
Assured Product Integrity: Most products are packaged in amber vials with septa to ensure product integrity as well as offer ease of dilution and use for imaging experiments. Product is packaged with fine tolerances to minimize the need to weigh substrates.
Flexibility and Convenience: Available in multiple sizes to accommodate a variety of experimental settings.
References
Welsh, D.K. and Kay, S.A. (2005) Curr. Opin. Biotechnol.16, 73–8.
Kaijzel, E.L. et al. (2007) Clin. Cancer Res.13, 3490–7.