The amine-reactive Marina Blue® succinimidyl ester can be used to create blue-fluorescent bioconjugates. Based on the 6,8-difluoro-7-hydroxycoumarin fluorophore, Marina Blue® dye exhibits bright blue fluorescence emission near 460 nm and is optimally excited by the intense 365 nm spectra line of the mercury-arc lamp. Because the pKa values of Marina Blue® derivatives are 2-3 log units lower than those of the corresponding 7-hydroxycoumarin conjugates, Marina Blue® conjugates are strongly fluorescent even at neutral pH.
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For Research Use Only. Not for use in diagnostic procedures.
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