TANGO M1-BLA U2OS CELLS KIT

• 产品编号：K1861      品牌：invitrogen       原厂货号：K1861
• 产品分类：生化和细胞分析 > 细胞分析试剂盒 > GPCR检测试剂盒
• 应用分类：行业及应用 > 药物研发 > 靶标和先导药物鉴定及验证 > G 蛋白偶联受体生物学G-Protein Coupled Receptor Biology (GPCR) > Cell-Based GPCR Reporter Assays > 试剂盒和分析 > 基于细胞的分析试剂盒 > 基于细胞的 GPCR 分析试剂盒
  　　　　　行业及应用 > 药物研发 > 靶标和先导药物鉴定及验证 > G 蛋白偶联受体生物学G-Protein Coupled Receptor Biology (GPCR) > Cell-Based GPCR Reporter Assays > Cell-Based GPCR Reporter Assays - G-Protein Coupled Receptors > 乙酰胆碱（毒蕈碱） > M1

描述：

Tango™ M1-bla U2OS cells contain the human muscarinic M1 receptor (CHRM1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin⁄TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element. The Tango™ M1-bla U2OS cells have been functionally validated for Z’ factor and EC50 concentrations of oxotremorine M. In addition, Tango™ M1-bla U2OS cells have been tested for assay performance under variable conditions.

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