M3-NFAT-BLA CHO-K1 CELLS 1 KIT

• 产品编号：K1716      品牌：invitrogen       原厂货号：K1716
• 产品分类：生化和细胞分析 > 细胞分析试剂盒 > GPCR检测试剂盒
• 应用分类：行业及应用 > 药物研发 > 靶标和先导药物鉴定及验证 > G 蛋白偶联受体生物学G-Protein Coupled Receptor Biology (GPCR) > Cell-Based GPCR Reporter Assays > 试剂盒和分析 > 基于细胞的分析试剂盒 > 基于细胞的 GPCR 分析试剂盒
  　　　　　行业及应用 > 药物研发 > 靶标和先导药物鉴定及验证 > G 蛋白偶联受体生物学G-Protein Coupled Receptor Biology (GPCR) > Cell-Based GPCR Reporter Assays > Cell-Based GPCR Reporter Assays - G-Protein Coupled Receptors > 乙酰胆碱（毒蕈碱） > M3

描述：

GeneBLAzer® M3-NFAT-bla CHO-K1 cells contain the human Acetylcholine (Muscarinic) Receptor 3 (M3) stably integrated into the CellSensor® NFAT-bla CHO-K1 cell line. CellSensor® NFAT-bla CHO-K1 cells (Cat. no. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.

The GeneBLAzer® M3-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of Carbachol. In addition, GeneBLAzer® M3-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

The M3 receptor is localized in smooth muscle, exocrine glands, and the central nervous system. M3 has been implicated in autoimmune and neurological disorders.

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注意事项：

For Research Use Only. Not for use in diagnostic procedures.