CALCR-CRE-BLA FS 293F CELLS COMBO

• 产品编号：K1480      品牌：invitrogen       原厂货号：K1480
• 产品分类：生化和细胞分析 > 细胞分析试剂盒 > GPCR检测试剂盒
• 应用分类：行业及应用 > 药物研发 > 靶标和先导药物鉴定及验证 > G 蛋白偶联受体生物学G-Protein Coupled Receptor Biology (GPCR) > Cell-Based GPCR Reporter Assays > 试剂盒和分析 > 基于细胞的分析试剂盒 > 基于细胞的 GPCR 分析试剂盒
  　　　　　行业及应用 > 药物研发 > 靶标和先导药物鉴定及验证 > G 蛋白偶联受体生物学G-Protein Coupled Receptor Biology (GPCR) > Cell-Based GPCR Reporter Assays > Cell-Based GPCR Reporter Assays - G-Protein Coupled Receptors > 降钙素 > CALCR

描述：

The GeneBLAzer® CALCR-CRE-bla Freestyle293 cells contain the CALCR receptor isoform (CTR2/CT(a)/CTRI1-), accession # NM_001742.2, stably integrated into the CellSensor® CRE-bla Freestyle293 cell line. The CellSensor® CRE-bla Freestyle293 cells contain a beta-lactamase (bla) reporter gene under control of the cAMP (CRE) response element.

CALCR-CRE-bla Freestyle293 cells have been tested for variable assay conditions, including DMSO concentration, cell number, stimulation time, and substrate loading time and functionally validated for Z' and EC50 concentrations of calcitonin. Additional testing data using alternate stimuli are also provided. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.

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