ON-TARGETplus GAPD Control pool (Human)

• 产品编号：D-001830-10-50      品牌：Dharmacon       原厂货号：D-001830-10-50
• 产品分类：DNA和RNA纯化 > RNA干扰 > RNA干扰对照 > RNAi阳性对照
• 应用分类：

描述：

ON-TARGETplus siRNA阳性对照产品（ON-TARGETplus Positive Control Reagents）

产品特点：

• 最佳设计和化学修饰技术确保具有更好的沉默特异性并降低脱靶效应。
• 实验验证可稳定、高效地沉默人、小鼠和大鼠细胞中高表达的持家基因（见下图）。
   

产品应用：

• 通过检测靶基因沉默效果可量化确认siRNA在人、小鼠和大鼠细胞的转染效率。
• 可用于体内使用单条siRNA或者SMARTpool? 试剂基因沉默的阳性对照。

原厂资料：

Thermo Scientific ON-TARGETplus GAPD Control siRNA is a validated positive control, guaranteed to silence GAPD in human, mouse, or rat cells. The ON-TARGETplus siRNA patented dual-strand modification pattern reduces off-targets by up to 90%, allowing improved specificity.

Also known as glyceraldehyde-3-phosphate dehydrogenase or GAPDH, GAPD is an important enzyme in carbohydrate metabolism that is well conserved across the animal kingdom. This gene is abundantly expressed in most cells and because it is non-essential, knockdown of the corresponding mRNA does not affect cell viability.

Highlights
• Validated positive controls siRNA for guaranteed silencing of GAPD
• Reduced off-targets due to the ON-TARGETplus dual-strand modifications
• Targets accession number NM_002046 (human) or NM_008084 (mouse) or XM_575242 (rat)