siSTABLE® 阴性对照试剂 (siSTABLE® Negative Control siRNA Reagents)
产品描述：
BLAST序列比对分析确保至少与任何已知的人、小鼠和大鼠基因4个碱基错配；
特殊的siSTABLE化学修饰技术显著提升siRNA稳定性；
产品应用：
是siSTABLE化学修饰siRNA试剂的最佳对照；
将序列特异性效应和非特异性效应有效区分。
原厂资料：
Thermo Scientific siSTABLE Non-Targeting siRNA #1 was designed to have a minimum of four mismatches to all human, mouse, and rat genes to avoid non-specific silencing due to off-targets. This negative control siRNA is chemically modified to significantly extend siRNA stability an is recommended for use as a negative control in experiments using siSTABLE modified siRNA against a target gene or where increased stability of the control is desired.
Highlights
• BLAST analysis confirms at least 4 mismatches with all known human, mouse, and rat genes
• Chemically modified to significantly extend siRNA stability
• Recommended for use as a non-specific control in experiments using siSTABLE modified siRNA against the target gene or where increased stability of the control is desired
Experimental considerations
siRNA-mediated RNAi experiments should include non-targeting siRNA as a control for non-sequence-specific effects. Changes in mRNA or protein levels in cells or tissues treated with these controls reflect a non-specific baseline cellular response to which the levels in cells or tissues treated with target-specific siRNA can be compared.
To request a larger quantity or in vivo processing of this control product, please email Technical Support, or call 1-800-235-9880. International customers, please call 303-604-9499 or your local Sales Representative.
京公网安备11010802025653 版权所有：北京逸优科技有限公司
