siGENOME Cyclophilin B Control siRNA (Human/Mouse/Rat)

• 产品编号：D-001136-01-20      品牌：Dharmacon       原厂货号：D-001136-01-20
• 产品分类：DNA和RNA纯化 > RNA干扰 > RNA干扰对照 > RNAi阳性对照
• 应用分类：

描述：

siGENOME siRNA阳性对照：

产品特点：

对人，小鼠和大鼠高丰度表达的看家基因进行有效持久的沉默效果。

应用：

通过检测人、大鼠和小鼠目的基因的沉默效率来确定siRNA相应的转染效率。
为使用Individual siRNA和SMARTpool试剂进行体外研究实验提供了配套的工具。

siGENOME siRNA阴性对照：

产品特点：
无靶标的siRNAs产品或Pool产品设计时未针对人、大鼠和小鼠细胞的任何特定基因。
无靶标siRNAs已经通过微阵列验证在人源细胞中几乎无其靶向标的。
有RISC-Free siRNA供选择，对该产品进行化学修饰可降低其导入效率。
应用：

在人、大鼠和小鼠中确定siSTABLE individual siRNA的沉默特异性。
可从非特异性效应中区别出序列特异性沉默效应。

原厂资料：

Thermo Scientific siGENOME Cyclophilin B Control siRNA is a validated positive control, guaranteed to silence cyclophilin B in human, mouse, or rat cells. Thermo Scientific siGENOME positive control siRNA designs are highly functional, chemically synthesized, and mostly unmodified siRNA duplexes that allow positive silencing for validation of experimental design and detection methodologies.

Also known as peptidylprolyl isomerase B (PPIB), cyclophilin B is associated with the secretory pathway. This gene is abundantly expressed in most cells and because it is non-essential, knockdown of the corresponding mRNA does not affect cell viability.

Highlights
• Targets accession numbers: NM_000942 (Human) , NM_011149 (Mouse), and NM_022536 (Rat)
• Validated, unmodified positive control siRNAs deliver guaranteed silencing