GAPS™ II coated slides are manufactured from a proprietary ultraflat glass that enhances microarray performance, enabling more accurate reading of microarrays by confocal laser scanners. GAPS™ II coated slides provide the same coating process and attachment chemistry as original GAPS™ amino-silane coated slides, enabling researchers to use the same protocols they optimized for GAPS™ slides. Each case of GAPS™ II slides includes optimized protocols for use and troubleshooting hints.