Human Monkey Anti-Porcine Type II Collagen IgA Antibody Assay Kit, OPD

产品编号：Cd-2063 品牌：Chondrex 原厂货号：2063
产品分类：ELISA及其它免疫分析 > ELISA > ELISA检测试剂盒
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包装：

1 kit

运保温度:

-20°C

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描述：

IgA antibodies to type II collagen are often associated with IgG antibodies in human sera. Importantly, IgA and IgG antibodies share identical collagen types and species specificity in individual sera, suggesting that the same collagen is involved in eliciting these antibodies. Therefore, it is highly likely that heterologous collagen in diets may play a primary role in the anti-collagen antibody production, regardless of the disease. However, this does not indicate that only type II collagen is always the eliciting antigen, since type I collagen, found abundantly in diets, share amino acid sequences with type II collagen by more than 80% and the antibodies in human sera often react to both type I and type II collagen.To determine the diversity of anti-collagen antibodies in human sera, Chondrex provides IgA and IgG antibody assay kits with various species of type I and type II collagen-coated strips as well as uncoated wells . This ELISA kit contains enough materials to run two plates on two separate occasions (see assay procedure) and may be used for monkey sera as well as human sera.

注意事项：

Note: Since IgA and IgG antibodies in human sera share similar collagen types and species of specificity, it is assumed that IgA antibodies determined by this ELISA kit might be underestimated due to the competitive binding of IgG antibodies to the identical epitopes on collagen molecules. In order to determine accurate IgA antibody levels in human serum samples, it is recommended to treat serum samples with Protein G to remove IgG antibodies.