Recombinant TNF-α is a bioactive protein intended for use in cell culture applications. TNF-α causes cytolysis and cytostasis of many tumor cell lines. TNF-α has a wide spectrum of activities, including chemotaxis of neutrophils, alteration of the endothelium, inhibition of anticoagulatory mechanisms, and promotion of angiogenesis. ED50 range = 0.02 to 0.05 ng⁄mL (Specific Activity: 2 x 10^7 to 5 x 10^7 units⁄mg), determined by the dose dependent cytotoxic effect on L929 cells in the presence of actinomycin D.
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注意事项：
Lyophilized protein can be stored at 2-8°C dessicated. Once reconstituted, store in aliquots at ≤20°C. Avoid multiple freeze⁄thaw cycles.
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