MRPL11 Antibody

• 产品编号：CST-2199S      品牌：CST       原厂货号：2199S
• 产品分类：抗体 > 一抗 > 蛋白特异性一抗
• 应用分类：

描述：

MRPL11 Antibody检测内源性MRPL11总蛋白水平。通过人工合成人源MRPL11蛋白相应序列的多肽片段去免疫动物从而制备多克隆抗体。通过蛋白A和多肽亲和层析纯化抗体。一部分线粒体蛋白是在线粒体里的核糖体中合成的 (1)。 55S哺乳动物线粒体核糖体是由28S小亚基和39S大亚基组成(1)。在人类线粒体核糖体的大亚基中已鉴定超过40个蛋白质组分(1)。Mitochondrial ribosomal protein L11 (MRPL11)就是这个组分中的一个 (1)。在动物、植物和真菌中，这个蛋白质由核内基因组中的一个基因翻译而来的(2)。

1. Koc, E.C. et al. (2001) J Biol Chem 276, 43958-69.
2. Handa, H. et al. (2001) Mol Genet Genomics 265, 569-75.

原厂资料：

Specificity / Sensitivity

MRPL11 Antibody detects endogenous levels of total MRPL11 protein.

Source / Purification

Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human MRPL11. Antibodies are purified by peptide affinity chromatography.

Background

A subset of mitochondrial proteins are synthesized on the ribosomes within mitochondria (1). The 55S mammalian mitochondrial ribosomes are composed of a 28S small subunit and a 39S large subunit (1). Over 40 protein components have been identified from the large subunit of the human mitochondrial ribosome (1). The mitochondrial ribosomal protein L11 (MRPL11) is one such component (1). In animals, plants and fungi, this protein is translated from a gene in the nuclear genome (2).

1. Koc, E.C. et al. (2001) J Biol Chem 276, 43958-69.
2. Handa, H. et al. (2001) Mol Genet Genomics 265, 569-75.

注意事项：

For Research Use Only. Not For Use In Diagnostic Procedures.

Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM
NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C.
Do not aliquot the antibody