Description: The mouse IL-22 ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of mouse IL-22. The mouse IL-22 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
IL-22 is a cytokine originally identified as a gene induced by IL-9 in murine T lymphocytes, and showing 22% amino acid identity with IL-10.
IL-22 is produced by activated Th1 and NK cells acting primarily on epithelial cells and is involved in inflammatory responses. Neither resting nor activated immune cells express IL-22 receptor, and IL-22 does not have any effects on these cells in vitro and in vivo. In contrast, cells of the skin and the digestive and respiratory systems represent putative targets of this cytokine. Thus IL-22 does not serve the communication between immune cells but is a T cell mediator that directly promotes the innate, nonspecific immunity of tissues. IL-22 serves as a protective molecule to counteract the destructive nature of the immune response to limit tissue damage.
Components
Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to mouse IL-22
Biotin-Conjugate anti-mouse IL-22 antibody
Streptavidin-HRP
Mouse IL-22 Standard lyophilized, 500 pg/ml upon reconstitution
Sample Diluent
Calibrator Diluent
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Red-Dye
Adhesive Films
京公网安备11010802025653 版权所有：北京逸优科技有限公司
